While West, 43, has created quite a stir in the weeks since his announcement, he's hardly the first star to set his sight on politics.
A handful of stars have tried to make a play at the White House, but many others have aimed to take office in a more local capacity.
Here's a look at some celebrities who have stepped outside of the glitz and glam of Hollywood and made their mark -- or at least tried -- by running for political office.
In an interview with Forbes earlier this month, the "Gold Digger" rapper admitted that he'd run as a Republican if Trump weren't running, but since the slot is occupied, he's running under a new party called "The Birthday Party."
The musician held his first campaign rally in North Charleston, S.C., on Sunday, although he won't appear on the state's ballot and potentially many other states if he doesn't submit signatures on time.
West’s home state of Illinois could see him on the presidential ballot in November however. Four minutes before the deadline, two representatives filed 412 petition sheets with election officials, a spokesperson previously confirmed to Fox News.
Nixon, now 54, ran as a staunch progressive and became known for embracing the term "unqualified lesbian," which is what Christine Quinn, the former speaker of the New York City Council, called the actress during the race.
Cuomo defeated Nixon by a wide margin.
"American Idol" season two runner-up Clay Aiken took a stab at politics in 2014 when he announced his run for congress in North Carolina.
Aiken's Democratic opponent, Keith Crisco, died just a day before Aiken, now 41, was declared the primary winner by a narrow margin.
"I am stunned and deeply saddened by Keith Crisco’s death. Keith came from humble beginnings," Aiken said at the time. "No matter how high he rose -- to Harvard, to the White House and to the governor's cabinet -- he never forgot where he came from."
Despite his win in the primary, Aiken lost the general election to Republican incumbent Renee Ellmers.
The actor, now 72, ran for governor of California in 2003 when Democratic Governor Gray Davis was recalled. He became known as the "Governator" and won the election with relative ease.
Schwarzenegger was re-elected in 2006 and served until the end of his term, and is the most recent Republican governor of the state.
Known widely as an expert actor, director and producer, winning a mayoral race is also on Clint Eastwood's list of accolades.
The star was elected to the office of mayor in Carmel-by-the-Sea, Calif., in 1986 by a landslide with over 72 percent of the votes.
He served for two years and did not seek re-election. The actor's political alignments have been all over the map, as he's previously endorsed both Mitt Romney and Mike Bloomberg in their respective presidential bids.
In 1994, Howard Stern announced that he'd be running for the office of Governor in the state of New York.
The iconic radio personality, now 66, ran as a libertarian and had three major goals, per Reason Magazine: Reinstate the death penalty, stagger tolls to reduce traffic, and carry out roadwork through the night.
The most peculiar part of his political promise, however, was his intention to step down upon completing his three goals.
Stern dropped his bid after refusing to provide financial documents that disclosed his income.
Jesse "The Body" Ventura
After that, Ventura, now 69, was elected governor of the state in 1998 as a member of the Reform Party. He broke with the Reform Party a year later and did not run for re-election.
In April, he said he's now considering a potential presidential run.
A hugely popular child star in her day, Shirley Temple also had aspirations outside of Hollywood.
Temple wrapped up her showbiz career with a 1963 episode of "The Red Skelton Hour" before diving into politics in 1967 with a run at a congressional seat in Calif.
Despite losing the election, Temple would go on to serve as the US Ambassador to Ghana and Czechoslovakia. She also became the first woman to serve as Chief of Protocol, which she did alongside Gerald Ford.
Now known as one of Hollywood's most conservative voices, Roseanne Barr once tried to take the White House, albeit from a much different stance than she takes today.
In the 2012 election, Barr ran as a candidate for the left-wing Peace and Freedom Party.
The FEC reported that Barr, now 67, came in 7th place in the election, amassing over 67,000 votes.
Barr's campaign was chronicled in the documentary "Roseanne for President!" and she is now known as one of Trump's biggest celebrity supporters.
According to Time, Bono encountered "local government red tape over his home and an Italian restaurant he owned," which prompted him to run for office.
The star snagged the mayoral office of Palm Springs, Calif., serving from 1988 to 1992. He'd go on to earn a seat in the House of Representatives, where he served until 1998.
"Saturday Night Live" alum Al Franken set his sight on politics after finding success in Hollywood.
Before running for Senate, Franken, now 69, was a comedy writer, actor, author and radio talk show host for 37 years when he was elected in a nail-biting Senate election against Republican incumbent Norm Coleman. Franken’s comedy career included time as a writer and performer for NBC’s “Saturday Night Live.”
Franken would hold his senate seat from 2009 until his 2018 resignation in light of sexual misconduct allegations.
It's easy to forget that President Ronald Reagan was a Hollywood star before making a run at the presidency.
Reagan had forged a successful career in both film and television with 82 acting credits to his name. His wife, Nancy, was also an actress.
Reagan would first serve as Governor of Calif. from 1967-1975 before serving as president from 1981-1989.