The three American astronauts and one German in the capsule left the ISS Thursday, after spending nearly a week with their replacements. SpaceX brought up their U.S. and Italian replacements last week, after completing a charter trip to the station for a trio of businessmen.
The astronauts aboard the Dragon capsule were NASA's Crew-3 commander Raja Chari, pilot Thomas Marshburn and mission specialist Kayla Barron, along with mission specialist Matthias Maurer of the European Space Agency, according to Space.com.
"That was a great ride," said Chari. As for the reintroduction to gravity, he noted: "Only one complaint. These water bottles are super heavy."
NASA is expected to have the Crew-3 astronauts back in Houston later Friday morning.
During their time in space, the astronauts conducted three spacewalks and performed multiple science experiments.
The ISS is now under the control of Russian cosmonaut Oleg Artemyev. He is overseeing a crew that includes Russian cosmonauts Denis Matveev and Sergey Korsakov and NASA's Crew-4 astronauts Kjell Lindgren, Bob Hines, Jessica Watkins and Samantha Cristoforetti of the European Space Agency.
Russia's war with Ukraine has caused tensions between the U.S. and Russia, but astronauts aboard the ISS have described it as a "place of peace." The new ISS commander, Russian cosmonaut Oleg Artemyev, described his crewmates as brothers and sisters.
SpaceX, owned by billionaire Elon Musk, has now launched 26 people into orbit in less than two years, since the company started ferrying astronauts for NASA. Eight of those 26 were space tourists.
The Associated Press contributed to this report.