Sunday, 1 p.m. EDT, Fox

OPENING LINE - Panthers by 14

RECORD VS. SPREAD - San Francisco 1-0, Carolina 0-1

SERIES RECORD - Panthers lead series 11-8

LAST MEETING - 49ers beat Panthers 23-10, divisional playoff, Jan. 12, 2014

LAST WEEK - 49ers beat Rams 28-0; Panthers lost to Broncos 21-20

AP PRO32 RANKING - 49ers No. 26, Panthers No. 5

49ERS OFFENSE - OVERALL (21), RUSH (5), PASS (27).

49ERS DEFENSE - OVERALL (2), RUSH (t-7), PASS (2).



STREAKS, STATS AND NOTES - San Francisco looks to begin season 2-0 for first time since 2012. ... Blaine Gabbert had QB rating of 135.9 in fourth quarter vs. Rams. He's thrown TD pass in 11 straight games. ... 49ers offensive line didn't allow sack vs. Rams. ... RB Carlos Hyde ran for 88 yards and two TDs in season opener. ... WR Jeremy Kerley had seven catches for 61 yards in 49ers debut. ... 49ers' defense limited Rams to 185 yards and 10 first downs in shutout. ... LB NaVorro Bowman led 49ers with nine tackles and had INT vs. Rams. Bowman had 11 tackles in playoff win vs. Carolina in 2014. ... LB Ahmad Brooks has sack in three of last four games. With next sack Brooks moves into tie with former DT Dana Stubblefield for third in franchise history... Panthers were 10-0 at home in 2015, including 2-0 in playoffs. ... QB Cam Newton has NFL-record 32 career games with both TD passing and TD rushing. He has more TDs rushing than any QB in NFL history. ... Panthers had 158 yards rushing vs. Denver, marking 28th consecutive regular season game with at least 100 yards rushing. ... RB Jonathan Stewart had at least 75 yards from scrimmage in eight of last 10 games. ... TE Greg Olsen has five TD catches in last seven home games. ... Panthers' defense forced three Denver turnovers after leading NFL in that category in 2015 with 39. ... Carolina secondary struggled with tackling in loss to Denver. ... CB Bene Benwikere got start vs. Denver over rookie Daryl Worley and had INT. ... Since entering NFL in 2012, MLB Luke Kuechly leads NFL with 601 tackles. Fantasy Tip: WR Kelvin Benjamin had six catches for 91 yards and TD last week in first game back from torn ACL. Benjamin was targeted team-high 12 times and played 52 snaps.


AP NFL website: www.pro32.ap.org and http://twitter.com/AP-NFL