Rescue crews in Missouri are racing against time to find survivors of the deadliest tornado in nearly six decades while forecasters predict more violent storms could hit the region.
The death toll in Joplin, Mo., reached 122 on Tuesday, authorities said, with over 750 injured. Rescuers so far pulled 17 people from the rubble, and Gov. Jay Nixon vowed that crews would keep searching until everyone is accounted for.
"They still think there are folks that could be alive," Nixon said.
Searchlights were brought in for work to continue overnight. As search and rescue crews dig through the rubble Tuesday, residents are bracing for more potentially deadly weather that could include tornadoes in Oklahoma, Kansas, Texas, Arkansas and Missouri.
The National Weather Service's Storm Prediction Center said the highest risk area for severe weather Tuesday extends from south-central Oklahoma to south-central Kansas.
The prediction center says there is a moderate risk of severe weather that could include tornadoes extending from northern Texas, across much of Oklahoma to central Kansas, and into western Arkansas and southwestern Missouri, which includes Joplin.
The severe weather could also include wind gusts of 55 to 75 mph and nearly baseball-sized hail.
The killer tornado that struck Joplin, a blue-collar southwest Missouri town of 50,000 people, slammed straight into St. John's Regional Medical Center. The hospital confirmed that five of the dead were patients -- all of them in critical condition before the tornado hit. A hospital visitor also was killed.
The tornado destroyed possibly "thousands" of homes, Fire Chief Mitch Randles told the Associated Press. It leveled hundreds of businesses, including massive ones such as Home Depot and Walmart.
Speaking from London, President Obama said he would travel to Missouri on Sunday to meet with people whose lives have been turned upside down by the twister. He vowed to make all federal resources available for efforts to recover and rebuild.
"The American people are by your side," Obama said. "We're going to stay there until every home is repaired, until every neighborhood is rebuilt, until every business is back on its feet."
Craig Fugate, director of the Federal Emergency Management Agency, told NBC's "Today" show Tuesday that Obama has declared a disaster in the area, which means residents are eligible for his agency's assistance.
"We're here for the long haul, not just for the response," Fugate said.
It was the second major tornado disaster in less than a month. In April, a pack of twisters roared across six Southern states, killing more than 300 people, more than two-thirds of them in Alabama.
In Joplin, much of the landscape was changed beyond recognition. House after house was reduced to slabs, cars were crushed like soda cans and shaken residents roamed streets in search of missing family members.
The danger was by no means over. Fires from gas leaks burned across the city. The smell of ammonia and propane filled the air in some damaged areas. And the forecast looked grim.
The April tornadoes that devastated the South unspooled over a three-day period starting in the Plains. The Storm Prediction Center in Norman, Okla., said a repeat could be setting up, with a possible large tornado outbreak in the Midwest on Tuesday and bad weather potentially reaching the East Coast by Friday.
"This is a very serious situation brewing," center director Russell Schneider said.
Heavy rain fell from dark skies all day Monday, finally letting up only as night fell, and lightning was so frequent that it slowed the rescue and recovery effort, Randles said. A police officer from Riverside, Mo., who was helping with the rescues, was burned from a lightning strike and hospitalized. Another officer was slightly injured in a near-lightning strike but kept working.
The rainy, cool weather -- the forecast called for an overnight low of 62 degrees -- raised concerns about its effect on anyone still trapped in rubble. A whipping wind, perhaps strong enough to finish off homes left barely standing by the tornado, made things more dangerous for searchers and potential survivors.
The twister that hit Joplin was one of more than 50 reported across seven Midwestern states over the weekend. One person was killed in Minneapolis and another in Kansas, but Missouri took the hardest hits.
At the destroyed Walmart, perhaps 200 cars lay crumpled in the parking lot. They were among thousands of shattered vehicles throughout the city, including dozens of tractor-trailers tossed on their sides or tops.
Kim Weathers, 48, looked at her black GMC Envoy and could only shake her head -- a piece of the roof from the Walmart had pierced the windows and crushed the side of the SUV.
"We were in the store and all of a sudden somebody yelled, `Get down!' Weathers said. "I could feel the wind coming, then stuff was flying, hitting me in the head. I looked up and it was outside -- the roof was gone."
St. John's took a direct hit, leaving debris dangling from the top of the structure and blowing out almost every window. The city's other hospital, Freeman, was overflowing with patients, and makeshift hospitals and triage areas were set up at several other locations. More than 400 people were treated for injuries, Randles said.
Unlike the multiple storms that killed more than 300 people last month across the South, Joplin was smashed by just one exceptionally powerful tornado. Not since a June 1953 tornado in Flint, Mich., had a single twister been so deadly. That storm also killed 116, according to the National Weather Service.
Nixon did not want to guess how high the death toll in Joplin would eventually climb. But he told AP: "Clearly, it's on its way up."
While many residents had up to 17 minutes of warning, rain and hail may have drowned out warning sirens. Some residents said the sirens are so common in "Tornado Alley" that they pay them little heed.
Nancy Hood, 63, is bedridden, suffering from diabetes and cancer. She said she often ignores warning sirens, but didn't on Sunday, telling her husband to grab their two grandsons, ages 4 and 7, and get to the hallway. The tornado destroyed most of Hood's house -- except the bedroom where she remained and the hallway.
"Praise God," Hood said. "It was divine intervention."
As rescuers toiled in the debris made soggy by the latest storm, they moved gingerly around downed power lines, large chunks of jagged metal, and boards with nails sticking out. Fires, gas fumes and unstable buildings also posed threats.
Teams of searchers fanned out in waves across several square miles. The groups went door to door, making quick checks of property that in many places had been stripped to their foundations or had walls collapse. Some condemned homes were spray-painted with a big "X."
The National Weather Service said the tornado was given its highest rating: EF5, with winds greater than 200 mph. At times, it was three-quarters of a mile wide.
The tornado got the attention of those who suffered in the South, including in Tuscaloosa, Ala., at the epicenter of the April storm.
"We're praying for those people," said retired Marine Willie Walker, whose Tuscaloosa home suffered more than $50,000 in damage. "We know what they're going through because we've been there already."
Once the center of a thriving mining industry, Joplin flourished though World War II because of its rich lead and zinc mines. It also gained fame as a stop along Route 66, the storied highway stretching from Chicago to Santa Monica, Calif., before freeways diminished the city's importance.
The community, named for the founder of the area's first Methodist congregation, is now a transportation crossroads and manufacturing hub. It's also the hometown of poet Langston Hughes and "Gunsmoke" actor Dennis Weaver.
City Manager Mark Rohr said the city "will recover and come back stronger than we are today."
Buck Nordyke, 53, planned to stay in his south Joplin home to ride out the rest of the storms, even though he's without power and has some slight roof damage.
"We could go to a neighbor's house or a hotel," Nordyke said. "But what about the next day, or what about the next day?"
The Associated Press contributed to this report.