Some of the biggest names in boxing have been speaking about the hotly anticipated bout scheduled for 12 rounds at the MGM Grand Garden Arena:
* Sugar Ray Leonard, one of the greatest boxers ever and seven-times world champion. "I give the edge to Mayweather. How can I not based on his unblemished record? Mayweather is the man to beat and if there were any fighters that I thought had a chance to beat Floyd Mayweather, one would be Shane Mosley. An intriguing fight."
* Mexican Juan Manuel Marquez, five-times world champion who was comprehensively beaten by Mayweather in his most recent bout in September. "This fight will be a real welterweight contest. Mosley can win if he is capable of closing Floyd's exits and using his speed along with his power."
* Britain's undefeated world super-middleweight champion Joe Calzaghe, who retired from boxing in February 2009. "I think it's a 50-50 fight. It's the most dangerous fight Mayweather has ever had. Mosley could upset him but I think it will be close."
* Renowned trainer Angelo Dundee, who has worked with Muhammad Ali, Sugar Ray Leonard and George Foreman. "Mayweather will have his toughest fight yet against Mosley, who came up the ranks and fought every tough Mexican. Mosley's stronger and more mature than anyone Mayweather has ever faced. While Mayweather is truly a one-of-a-kind fighter, I would have to give the edge to Mosley by decision."
(Compiled by Mark Lamport-Stokes; editing by Pritha Sarkar)