Police arrived around 2:30 p.m. Saturday to find one person dead at the scene of the two-car crash at North Columbia Boulevard and Peninsular Avenue, KPTV reported. Five others, including three children, were taken to the hospital with injuries.
Another person was located nearby and was also transported to the hospital.
The conditions of the individuals involved in the crash remains unknown at this time.
North Columbia Boulevard, the site of the crash, will be closed off during the investigation into the incident.
Saturday's crash was the 21st car-related death in Portland this year.