LONDON (Reuters) - Another John Isner marathon briefly looked possible at Wimbledon Thursday before the towering American was bundled out in the second round by Spain's Nicolas Almagro in four sets.

Isner returned to Court 18, which now boasts a plaque to commemorate last year's record-shattering 11-hour epic win against Nicolas Mahut, but was beaten 7-6 7-6 6-7 6-3.

Isner had beaten Mahut in a much-hyped rematch in the first round but was never able to make much impression against the hard-hitting 16th seed Almagro.

He served 28 aces but did not have a single break point on the Spaniard's serve. Almagro claimed the only break of the match early in the fourth set as he went on to seal a third round encounter with Russian Mikhail Youzhny.

(Reporting by Martyn Herman, editing by Mark Meadows)