Rome, Italy (SportsNetwork.com) - Roma and Inter Milan will meet at the Stadio Olimpico on Saturday for a Serie A clash with massive implications for both sides.

The Roman club enters the weekend in second place where it sits nine points back of Juventus.

But while Roma has a game in hand, time is running out for Rudi Garcia's side to make a move for the Scudetto.

There will be plenty on the line for Inter at the Stadio Olimpico, as well.

The Nerazzurri are vying for a place in Europe next season, and with the club sitting 11 points back of Napoli in the final Champions League spot, qualification looks unlikely.

That could mean the end for Walter Mazzarri's reign at the San Siro. Inter has employed six different managers since Jose Mourinho's departure in 2010, and it's possible that Mazzarri's tenure could be reduced to just one season in charge if the Nerazzurri miss out on Europe's top club competition yet again.

Inter comes into the round on a three-game unbeaten run, but its four losses in its last 10 league outings have dropped the club to fifth place in the table.

Roma, meanwhile, has lost just one Serie A match all season but must rely on Juventus to drop points at AC Milan on Sunday if Garcia's men hope to close the gap.

At the opposite end of the Serie A table, Sassuolo has lost 10 of its last 11 league matches, including its last six, to remain rooted to the foot of the table on 17 points. The club will hope to rebound on Sunday when it welcomes Parma to the Citta del Tricolore.

Bologna and Sampdoria are not in great form, either. Both clubs have suffered back-to-back defeats in their last two Serie A outings but will attempt to right their respective ships on Sunday with road matches at Hellas Verona and Torino.

Napoli and Fiorentina, separated by six points in the table, remain in contention for the final Champions League berth out of Italy. The two sides return to league action Sunday as Napoli heads to the Stadio Armando Picchi to face Livorno while Fiorentina hosts Lazio at the Stadio Artemio Franchi.

Also on Sunday, Atalanta welcomes Chievo to the Atleti Azzurri d'Italia and Catania heads to the Stadio Luigi Ferraris to square off with Genoa.