Josh Nunes tossed a trio of touchdowns to lead No. 25 Stanford to a 50-13 rout of Duke on Saturday at Stanford Stadium.

Nunes, making his second start in the post-Andrew Luck era, went 17-of-31 for 280 yards and an interception for Stanford (2-0), which snuck past San Jose State, 20-17, to open the season.

Stepfan Taylor carried the ball 15 times for 78 yards and a score, while Levine Toilolo, Drew Terrell and Jamal-Rashad Patterson each added a receiving score.

Sean Renfree started for Duke (1-1) and passed for 198 yards and a pair of interceptions on 28-of-40 passing. Backup Anthony Boone added 146 yards and an interception on 13-of-21 passing for the Blue Devils, who defeated FIU last weekend.

Jamison Crowder hauled in 10 passes for 111 yards and Desmond Scott added 11 grabs for 80 yards in the setback.