San Diego, CA (SportsNetwork.com) - Brandon Morrow pitched six good innings and Justin Upton hit a go-ahead two-run single, leading the San Diego Padres to a 4-2 win over the Colorado Rockies on Saturday night.

After Morrow (2-0) gave up two runs, seven hits and one walk in six innings, Brandon Maurer and Craig Kimbrel retired the last nine Colorado batters to seal the win.

Maurer threw two perfect innings and Kimbrel struck out two in a 1-2-3 ninth for his seventh save of the season.

The Padres have won the first two games of the three-game series after being swept by Houston.

"I thought we played a clean game all the way around," said Padres manager Bud Black. "I thought Morrow was good. These are the types of games you have to win."

Charlie Blackmon hit a solo homer for the Rockies, who have dropped four in a row.

"Certainly didn't get the timely hit," Rockies manager Walt Weiss said.

Colorado starter Jorge De La Rosa (0-2) suffered his second loss to the Padres this season after giving up three runs on five hits and three walks in five innings. He struck out nine.

Wil Myers drew a leadoff walk in the bottom of the first inning for San Diego and scored after consecutive singles from Derek Norris and Matt Kemp.

The Rockies tied the score in the top of the second after Carlos Gonzalez walked with one out, went to third on Nick Hundley's single and came home on a groundout by DJ LeMahieu.

They took a 2-1 lead on Blackmon's leadoff blast over the center field wall in the top of the third, his third homer of the season, but it didn't last.

After Myers drew a leadoff walk and Norris followed with a double in the fifth inning, Upton drove them in with a single to give the Padres a 3-2 edge.

They extended it with a run off reliever Brooks Brown in the sixth inning after Clint Barmes hit a two-out single, went to second on Will Venable's walk and scored on Myers' single.

The Rockies had runners at first and second base in the sixth inning after singles by Troy Tulowitzki and Gonzalez but Morrow escaped, getting Hundley on a ground ball.

Game Notes

Morrow got his first win in four career starts against the Rockies ... De La Rosa gave up nine runs -- seven earned -- in two innings against San Diego on April 20 after being activated from the disabled list.