Busch, the series points leader coming into the race, passed Johnson with about a dozen laps remaining and was opening up a comfortable margin when his brother Kurt scraped a wall, forcing a caution from laps 198-201. The yellow flag erased much of Busch's lead, but he was able to fight off a quick move from Johnson after the restart and pull away.
Brad Keselowski finished third, his third consecutive top-three finish and fifth top-10 in his last six races. Mark Martin was fourth.
It was the 23rd Sprint Cup win of Busch's career.