Genoa fired manager Alberto Malesani for the second time this season following Sunday's 4-1 defeat against Siena and has replaced him with Luigi De Canio.

Malesani was sacked for the first time in December with Genoa sitting in 10th place in the Serie A table.

But his successor, Pasquale Marino, fared worse than Malesani as the club slipped to 16th in the league on his watch.

Malesani was brought back on April 2 to help steer Genoa away from the relegation zone, but two draws and a loss have left the club just one point and one place above the bottom three with five games to go.

De Canio managed at Genoa in 2004 and will take charge of his first match on Wednesday at AC Milan.