No timetable for surgery on his anterior cruciate ligament has been set but it will take place in the near future, the Braves said in a release.
Estimated time of recovery for the six-times All-Star is about six months.
Despite his age, the 38-year-old told reporters Wednesday he would consider a comeback next season if surgery was required.
Jones was injured while making a throw from third base to first during Tuesday's game at Houston. He crumpled to the ground after landing on his left leg and eventually limped off the field.
Jones, who has played all 17 of his big-league seasons with the Braves, had surgery on the same leg before the 1994 campaign.
He had considered retirement earlier in the season while in a batting slump but his hitting had improved recently.
Jones was hitting .265 with 10 home runs and 46 RBIs, and ranks as the Braves' all-time career leader in games played, hits, home runs and RBIs.
(Reporting by Gene Cherry in Raleigh, North Carolina. Editing by Steve Ginsburg)