Columbus, OH – Adreian Payne scored a team-high 15 points as ranked Ohio State its first home loss in 48 decision at Value City Arena.
Keith Appling added 14 points and Draymond Green had 12 with nine rebounds for Michigan State (20-5, 9-3 Big Ten), which earned its third straight win and now sits in a tie with Ohio State for the top spot in the conference.
Jared Sullinger recorded 17 points and a season-high 16 rebounds for Ohio State (21-4, 9-3), but also had a career-high 10 turnovers in the Buckeyes' first loss in Columbus since February 17, 2010. They were riding a 39-game home win streak entering Saturday's contest.
Aaron Craft dropped in 15 points in a losing effort as Ohio State shot just 26.4 percent from the floor in the contest, including a 2-for-15 mark from three-point range.
After Payne's layup gave Michigan State an early 4-2 lead, Ohio State reeled off seven straight points. But Green's three-pointer halted the spurt and sparked a 7-1 swing by the Spartans to take a slim, 11-10, lead.
A pair of Sullinger free throws put the Buckeyes back on top before an 11-4 run by Michigan State put them ahead, 22-16, as Ohio State failed to make a shot from the floor for over nine minutes.
Sullinger's trey stopped Ohio State's offensive drought and brought the Buckeyes within three, but the Spartans recorded the game's next six points to take their largest lead of the game to that point, 28-19, with less than five minutes left in the first half.
The Buckeyes never got closer than six for the remainder of the half and trailed 35-25 at the break for their largest halftime deficit of the season.
Ohio State shot just 7-for-21 from the floor and turned the ball over eight times in the first half, while Michigan State went 15-for-32 and recorded 14 points off of the Buckeyes' giveaways.
Ohio State scored the first four points of the second half to close the gap to six, but the Spartans responded with six straight points to go ahead, 41-29, just past the four-minute mark of the half.
The Spartans held at least an eight-point lead over the next four minutes, but after Appling's layup gave Michigan State a 44-34 lead, Ohio State made a push, scoring six straight to get within 44-40.
Two Appling free throws then put Michigan State back up six, and after Ohio State missed four straight shots in succession in an offensive flurry, Derrick Nix's jumper stopped the Spartan's seven-minute streak without a basket from the floor.
Ohio State never threatened again from there, as the Spartans made enough free throws down the stretch.
Michigan State recorded its 12th 20-win season in the last 15 years...Ohio State fell to 5-3 against ranked opponents this season...The Spartans hold a 64-53 advantage in the all-time series...Michigan State shot 40.4 percent in the game and outscored Ohio State in the paint, 30-12.