The "Friends" alum, 51, took to Instagram on Monday to share the message, telling her fans: "Let’s put out the dumpster fire that is 2020."
She also encouraged people to "make a plan to vote early."
The actress also included a video from her bit with host Jimmy Kimmel at the Emmys Sunday evening, which featured Aniston -- wearing a vintage black Christian Dior dress -- using a fire extinguisher to put out a fire in a wastebasket.
Aniston, who was nominated for outstanding lead actress in a drama series, appeared front-and-center once more during the award show. This time around though, it featured Aniston with two of her former "Friends" co-stars: Lisa Kudrow and Courteney Cox.
When Kimmel, 52, checked in on Aniston to make sure she had made it home from doing the pair's first bit so she could be present for the announcement for her own category, the star replied: "I barely made it, but we're here."
Cox then appeared on the screen. "Courteney's there?" asked Kimmel. "Of course, I'm here. We live together," Cox, 56, replied.
"We’ve been roommates since 1994, Jimmy," added Aniston, referring to when "Friends" first aired in September 1994.
Kudrow then joined in. "Unbelievable," said Kimmel. "Lisa Kudrow, you live there too?"
Kudrow, 57, gave a simple response: "Yeah, where else would I live?"
Jason Bateman also made an appearance during the segment.