"An entire crew of road workers struck by a vehicle on 66WB," the rescue agency said.
Three people were riding in the SUV, two of whom tried to flee the scene before they were taken into custody, according to state police.
Arlington Fire said that an EMS task force of units from Arlington County and Fire and Fairfax County Fire and Rescue Department transported eight people to area trauma centers, including some with "critical injuries."
None of the injuries, however, appear to be life-threatening.
Officials told FOX5 the driver of the GMC has been arrested for DUI, and the crash remains under investigation. The roadway was closed for several hours as a result of the crash, but as since reopened for the morning rush hour.
The Virginia Department of Transportation’s NoVa District commented on the incident on Twitter with a simple message: stop driving drunk.
"We’re just not in the mood to post something cute," the agency said.
"This AM, a SUV crashed into our contractor’s work zone on I-66, sending 6 people to the hospital," VDOT continued. "So stop driving drunk, into work zones, hitting people, then trying to flee."