After making life difficult for Tampa Bay, Anaheim and Boston, the Orioles continued to play well against the playoff-bound Tigers in Thursday's opener, as Nolan Reimold's RBI single in the sixth inning proved to be the difference in a 6-5 win.
Adam Jones and J.J. Hardy homered in the victory, while Reimold added a sacrifice fly in the fourth for the Orioles, who have won eight of their last 10.
Baltimore starter Zach Britton (11-10) gave up five runs on six hits over five innings to pick up the win.
"A lot of teams will fold up after giving up a 5-0 lead, especially against a club like this," said Baltimore manager Buck Showalter. "But our guys showed their toughness tonight."
Delmon Young hit a three-run homer for the Tigers, who have lost two of three and are tied with the Texas Rangers, five games back of the AL East-champion New York Yankees for the best record in the American League.
Detroit starter Jacob Turner allowed five runs -- four earned -- on seven hits over three-plus innings. David Pauley (5-6) gave up one run on two hits over two relief frames to take the loss.
"We got some things we wanted to but we didn't get the win," said Detroit manager Jim Leyland. "You know, we bounced back and played good, but you have to give them the credit tonight."
Getting the call for the O's tonight will be righty Alfredo Simon, who is 4-9 with a 4.96 ERA. Simon lost his third straight decision on Sunday against the Angels, as he allowed six runs and eight hits in five innings.
This will be his second start against the Tigers, who reached him for four runs in a 4 2/3-inning no-decision back on August 12.
Detroit, meanwhile, will pin its hopes on righty Rick Porcello, who is 14-9 with a 4.79 ERA. Porcello lost for the first time in more than a month on Saturday in Oakland, as he surrendered three runs and nine hits in seven innings.
He is just 1-2 in three starts versus the O's with a 4.76 ERA in three starts.
Baltimore has won four of its seven games with the Tigers this season.