Updated

A fast-moving storm and lake-effect snow have led to school closings and travel troubles in the Northeast.

The latest round of lake-effect storms dumped up to 18 inches near Lake Erie's eastern shore. Blowing snow closed a nearly 60-mile stretch of the westbound lanes of the New York Thruway south of Buffalo on Wednesday.

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(John Hickey/Buffalo News)

Meanwhile, scores of business and government closings and delays were in effect across northern New England after the fast-moving system dumped more than a foot of snow.

Thousands of students in New York had Wednesday off.

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(John Hickey/Buffalo News)

In southwestern Pennsylvania, icy conditions may have been to blame for a seven-vehicle pileup on Interstate 70.

Officials say whiteout conditions were a factor in a deadly head-on crash south of Buffalo on Tuesday afternoon involving a tractor-trailer and an ambulance.