National Weather Service [NWS] officials said 13 confirmed tornadoes had appeared in Mississippi and Louisiana, the Clarion Ledger reported. The NWS announced earlier that at least two confirmed tornadoes hit Texas.
"Please cooperate with any emergency officials who may give instructions to you or your neighbors. More details to come," the city said. "Please pray for all!"
The National Weather Service had declared a tornado emergency for Monroe and the surrounding communities at 11:44 a.m. CDT as a confirmed "damaging" tornado was hitting the area.
City officials said additional damage was reported at one of the office buildings in the airport complex.
Another photo from the city showed damage at the airport, including several aircraft that appeared to be overturned.
Officials said due to weather conditions and debris removal from the runways, Mayor Jamie Mayo and Monroe Regional Airport Director Ron Phillips announced that “all flights at the Monroe Regional Airport are cancelled until further notice.”
Other images from the city revealed downed power lines in various areas.
The tornado that struck Monroe is part of a powerful storm system affecting the Easter holiday, bringing heavy rain, tornadoes and hail. The NWS' Storm Prediction Center said severe thunderstorms were likely into Sunday night, with the greatest threat in Louisiana through the Tennessee Valley.
The storm center said some 95 million people may be impacted by the storms. More than 5.8 million people live in the area where the most dangerous weather was most likely, including Birmingham, Ala., and Jackson, Miss.
“This could be a very difficult day weatherwise," Mississippi Gov. Tate Reeves noted in a video on Facebook. "Please be weather aware. Pay attention. I know that these storms that are coming through can be dangerous. We can see significant winds. We can also see significant tornadoes coming through Mississippi today.”
At midday, the weather service in Birmingham said radar showed strong storms moving into Alabama from Mississippi.
Fox News' Mike Arroyo and The Associated Press contributed to this report.