A week after a career-low passer rating Winston showed better command of the offense, completing 13 of 21 passes for 128 yards. Taysom Hill ran for a touchdown and Alvin Kamara rushed 24 times for 89 yards.
Patriots rookie quarterback Mac Jones entered the day hoping to stretch the field after two games in which the passing attack was mostly underneath. Instead, he found himself under pressure for most of the day and threw three interceptions, two leading to Saints touchdowns. New Orleans sacked Jones three times and hit him 11 times. He finished 30 of 51 for 270 yards and a touchdown.
Saints safety P.J. Williams returned Jones’ first pick of the day 46 yards to set up a 7-yard TD pass by Winston in the second quarter.
Jenkins was the beneficiary of the second INT, snaring a pass bobbled by tight end Jonnu Smith. He returned it 34 yards and put the Saints in front 21-3.
The Patriots cut it to 21-13 following Jones’ 22-yard TD pass to Kendrick Bourne with 9:22 left in the fourth period. The Saints responded with a 13-play, 75-yard drive that ate up 6:45 and ended with at 4-yard run by Hill that put them in front 28-13.
New Orleans overcame an early injury to take a 14-3 lead into halftime.
The Saints’ offensive line was already down one starter with center Erik McCoy (calf) ruled out. They lost another early in the first quarter after left tackle Terron Armstead exited with a left elbow injury.
But after going three-and-out on their opening drive, the Saints got efficient, sweeping down the field mixing runs and passes, and a long third-down conversion to get inside the red zone. Winston then put a bow on the 11-play, 69-yard drive with an 11-yard touchdown pass to Kamara.
The Saints turned defense into offense for their second score.
The Patriots had third down near midfield when linebacker Kaden Ellis pressured Jones, forcing a pass that was tipped and intercepted by Williams. He returned it 46 yards to the Patriots 9.
Three plays later Winston connected with Marquez Callaway for a 7-yard touchdown.
New England drove to the Saints 22 before a false start penalty forced it to settle for a 45-yard Nick Folk field goal.
Saints: Armstead left in the first quarter with a left elbow injury and was replaced by James Hurst.
Patriots: RB James White was carted off the field early in the second quarter with a hip injury after landing awkwardly as he was tackled by Damario Davis.
The Patriots held a halftime tribute to receiver Julian Edelman, who announced his retirement in April after 11 seasons.
The Super Bowl 53 MVP kicked off the ceremony with his trademark run out of the tunnel and sprint from end zone to end zone. Standing in front of representations for each of the three Patriots championships he was a part of, he said Foxborough would always hold a special place for his family.
"We lived you guys, we breathed you guys and we will die with you guys," he said.
Saints: host the Giants on Sunday.
Patriots: host former quarterback Tom Brady and the Buccaneers next Sunday.