A 4-year-old girl and two men have been killed and four others injured in a wrong-way crash in southern Michigan.

A pickup truck traveling eastbound in the westbound lanes of Interstate 94 in Marengo Township collided head-on about 12:30 a.m. Monday with a minivan, state police said.

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The 42-year-old driver of the pickup died at the scene. The 46-year-old minivan driver and a girl in that vehicle also died at the scene.

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Two men and a four-year-old girl were killed in a wrong-way crash on Interstate 94 in Michigan.

Another adult and three other children in the minivan were taken to hospitals with injuries that were not considered to be life-threatening, police said.

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State police said at least three children in the minivan were not in child safety seats or wearing seatbelts.

The names of the victims were not immediately released.

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Marengo Township is about 100 miles west of Detroit.