Amtrak and the United States Department of Transportation reports that all rail service south of Washington D.C. has been cancelled from Friday through Sunday, due to expected impact from Hurricane Irene.
Amtrak says that it will make further announcements regarding service as the storm progresses.
In addition, the Metropolitan Transportation Authorities warned Thursday that the hurricane may prompt a partial or full shutdown of services over the weekend, which New York City Mayor Bloomberg warned could last through Monday morning.
Airlines already began canceling flights Thursday and offering passengers the opportunity to rebook flights as they moved to get planes out of the way of the hurricane.
American Airlines and its American Eagle affiliate canceled 126 flights on Thursday.
Delta Airlines reported four cancelation and United airlines reported one.
Officials believe the storm will likely force hundreds of flights to be cancelled throughout the weekend.
The Associated Press contributed to this report.