Updated

A powerful storm system that produced multiple reports of tornadoes struck the Midwest early Wednesday, killing at least nine people in Illinois and Missouri.

Lt. Tracy Felty of the Saline County Sherriff's Office said six people were reported dead in the small town of Harrisburg, Ill., one of the areas hardest hit by the early morning storm. The apparent twister tore through the area around 5 a.m., causing widespread damage.

In Missouri, three people were killed -- one in a trailer park in the town of Buffalo, Fox News has learned. At least three people were critically injured in the small eastern Kansas town of Harveyville.

The National Weather Service has confirmed that the heavy damage in the southwestern Missouri town of Branson was caused by a 22-mile-long tornado.

The tornadoes were spawned by a powerful storm system that blew down from the Rockies on Tuesday and was headed across the Ohio and Tennessee river valleys toward the Mid-Atlantic region.

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Three people were reportedly killed in Tennessee after the storm system moved east, according to officials. Several others were reportedly trapped after their homes were destroyed near Crossville, Tenn.

Corey Mead, lead forecaster at the U.S. Storm Prediction Center in Norman, Okla., said a broad cold front was slamming into warm, humid air over much of the eastern half of the nation.

From Tuesday night into Wednesday morning, at least 16 tornado sightings were reported from Nebraska and Kansas across southern Missouri to Illinois and Kentucky, according to the storm center, an arm of the National Weather Service.

Jennifer Verhaalen, a long-term resident at the Hillbilly Inn Motel in downtown Branson, said she saw a white funnel cloud followed by a wall of rain as the storm closed in on the town around 1 a.m.

She said she retreated to a back bedroom with her husband as the storm slammed into two other hotel buildings tearing the roof off one.

Across the road, a strip mall lay in tatters, its roof missing and several walls collapsed. As the sun rose Wednesday, business owners picked through the remains of their stores.

Keith and Glenna Bartley, tourists from Kingsport, Tenn., said staff at the Grand Victorian Hotel where they were staying ushered them to the basement around 1:30 a.m.

Branson has long been a tourist destination for visitors attracted to the beauty of the surrounding Ozarks. But the city rose to prominence in the 1990s because of its theater district, which drew country music stars and other music celebrities including the Osmond twins and Andy Williams. It is about 110 miles southeast of Joplin, which was devastated by a monstrous twister last May that killed 161 people.

Farther north, rescue crews waited for sunrise to begin searching a trailer park south of Buffalo where at least one person was killed after an apparent twister slammed the area.

Lt. Dana Eagan of the Dallas County Sheriff's Office said 13 people at the park were hurt and the entire town was without power. Buffalo is about 35 miles north of Springfield.

Tornado season normally starts in March, but it isn't unusual to see severe storms earlier in the year. Forecasters can seldom assess how serious a season will be because twisters are so unpredictable. This year, two people were killed by separate tornadoes in Alabama in January, and preliminary reports have showed 95 tornadoes struck that month.

In neighboring Kansas, the National Weather Service reported brief tornado touchdowns southwest of Hutchinson, and Gov. Sam Brownback declared a state of emergency after an apparent tornado struck Harveyville.

The declaration covered Wabaunsee County, southwest of Topeka. The governor's office said one person was critically injured, several homes and a church were damaged and trees and power lines were down.

The system also skirted northern Arkansas, bringing gusts of up to 60 mph in the northwest. A wall cloud, which often produces twisters, was reported in Cherokee Village, where trees were scattered along roads, the weather service said. Residents of Clay County in northeastern Arkansas reported hail the size of golf balls, while half dollar-sized hail was reported in Mountain Home.

In northern Oklahoma, gusts of up to 80 mph flipped trailers and damaged homes near Cherokee.

Tornado warnings and watches were posted for most of Kentucky and a large portion of Kentucky.

The Associated Press contributed to this report. 

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