The Oakland Athletics had the AL's worst record a season ago and 2016 got off to a familiar start without their ace available.
They'll have to move another starter up to pitch Tuesday night when Chris Bassitt gets the ball as they continue a four-game home series with the Chicago White Sox.
Oakland went 68-94 a season ago for its worst season since 1997. The Athletics went 19-35 in one-run games in 2015 for the majors' second-worst record.
They were on the short end of such a decision in Monday's 4-3 loss in the opener without Sonny Gray, scratched from his opening day start because of food poisoning that sent him to the emergency room Monday morning for intravenous fluids. Gray will now start Wednesday.
Rich Hill, originally slated to start Tuesday, filled in and the 36-year-old was charged with all four runs in 2 2-3 innings in his club debut.
Oakland committed a major league-high 126 errors last year and had two on opening day, with Chicago capitalizing with two unearned runs.
''That's what happens when you give extra outs,'' manager Bob Melvin said. ''Can't do that. We learned that last year, we've learned it this spring. In close games it typically ends up being a play like that, a play or two defensively that you should make."
Now former White Sox right-hander Bassitt, who was 1-8 with a 3.56 ERA last year in 18 games - 13 starts for the Athletics, will face Chicago for the first time. Oakland dropped his last six outings, with Bassitt going 0-4 with a 5.40 ERA and getting a total of seven runs of support.
Bassitt went 1-1 with a 3.94 ERA in six games - five starts for Chicago as a rookie in 2014.
Melvin had to adjust his opening day lineup without Gray, inserting Stephen Vogt at catcher after Josh Phegley was originally going to catch the right-hander. The righty-swinging Phegley, who spent his first two seasons with the White Sox, will likely start Tuesday since Chicago is starting left-hander Jose Quintana.
The White Sox have won five straight at Oakland after a seven-game slide there.
All of Monday's scoring came in the third inning. Adam Eaton hit an RBI triple and Oakland native Jimmy Rollins drove in a run in his White Sox debut.
Jed Lowrie responded with a two-run single in the bottom half and scored on a hit by Danny Valencia before the Athletics managed three hits over the final six innings.
"The team today fought and clawed," Eaton said. "We had that big inning and then our pitching staff came in late in the ballgame and shut them down and that's all we can ask for."
Quintana had baseball's sixth-worst run support average at 3.62 a year ago as he went 9-10 with a 3.36 ERA. He was ninth in the AL with 177 strikeouts.
The left-hander has a 3.60 ERA in three starts against Oakland with no decisions. Billy Butler is 5 for 30 with 12 strikeouts against him and Valencia is 2 for 17.