Three players — White Sox starter Freddy Garcia (back), Tigers first baseman Miguel Cabrera (shoulder) and White Sox designated hitter Manny Ramirez (hand) — all left the game with injuries, while Chicago's Gordon Beckham (hand) was a late scratch from the lineup. Home plate umpire Angel Campos needed attention after being hit by a foul tip in the eighth inning, but stayed in the game.
The White Sox were trying to win the first eight games of a road trip for the first time since 1951, when they went 11-0 on a four-city jaunt. They fell behind in the first inning Tuesday and never caught up.
Verlander (15-8) allowed one run and walked one while striking out seven.
Detroit rookie reliever Robbie Weinhardt made things more interesting with a double error in the eighth when he misplayed a grounder and then threw the ball into the stands. Then he knocked Ramirez out of the game by hitting him with a pitch, but got out of the inning with a double play.
The Tigers broke the game open after Garcia was forced to leave with a stiff lower back. Garcia (11-6) allowed two runs in his two innings.
In reliever Lucas Harrell's first inning, the Tigers scored four unearned runs.
Harrell held the Tigers scoreless for the next three innings, but Chicago couldn't take advantage against Verlander. Brandon Inge finished the scoring with a three-run homer off Carlos Torres in the eighth.
Detroit took a 2-0 lead in the first on Damon's first homer since July 28, but Chicago got a run back in the third on Omar Vizquel's RBI single.
NOTES: The White Sox recalled Torres and INF Dayan Viciedo from Triple-A Charlotte before the game, bringing their roster to 32. ... Chicago's Paul Konerko (back) missed his third straight game. ... Cabrera, who has been bothered by shoulder tendinitis for the past week, left the game after six innings with the Tigers leading 6-1. ... A.J. Pierzynski of the White Sox extended his hitting streak to 14 games. ... Chicago reliever Gregory Infante and pinch-hitter Brent Morel both made their major league debuts.