After a scoreless first period, the Kings opened the scoring at the 6:19 mark of the second on the power play when Johnson's slap shot from the right point beat Niemi.
The Sharks, though, tied the game at the 11:39 mark of the second on Thornton's fourth goal of the year, a backhand shot from a sharp angle at the right side, and took a 2-1 lead less than a minute later on Marleau's fourth goal, a redirect of a Boyle shot.
Skating on the power play, San Jose made it a 3-1 game at 17:02 of the second. Joe Pavelski received a pass at the left side of the net, but lost control of the puck. It came out to the high slot where Boyle blasted it home.
At the 6:40 point of the third, the Sharks took a 4-1 lead as a left point shot was deflected on net and Couture was there to backhand home the rebound for his sixth goal of the season.
The Kings got one back less than two minutes later on the power play as Kopitar skated down the right wing and blasted a shot on net that was stopped, but he followed up his own shot and buried his second chance.
A late penalty to San Jose along with Quick being pulled allowed LA to skate 6-on-4 for the final 1:22, but the team was unable to pull any closer.
San Jose hosts Minnesota on Thursday...The Kings host Nashville on Tuesday...These teams split the six-game series last season...LA was 2-for-6 on the power play while San Jose went 1-for-6.