Joey Votto smacked the go-ahead solo home 2 game series at Great American Ball Park.

Jay Bruce and Edgar Renteria both cracked home runs and Paul Janish added a pair of hits for the Reds.

Mike Leake (10-7) gave up two runs on 11 hits over 7 1/3 innings while fanning five and walking one. Francisco Cordero worked a rocky ninth to earn his 21st save.

Troy Tulowitzki clubbed a home run while Chris Nelson and Seth Smith added two hits apiece for the Rockies, winners of three of their last five contests.

Kevin Millwood (0-1) took the loss in his first start in the majors since September of 2010 as a member of the Baltimore Orioles. He went seven innings, giving up three runs on six hits while fanning six and walking one.