Nashville, TN – Martin Erat scored with 8.4 seconds left in 5, at Bridgestone Arena.
The comeback nullified a hat trick from Blue Jackets forward Jeff Carter, who recorded all three scores in a first period which saw the visitors emerge with a 4-1 advantage.
David Legwand scored the tying goal with 3:46 remaining for the Predators, who have won six of their last seven.
Ryan Johansen notched the other two goals for the Blue Jackets, losers of four straight and six of seven.
Curtis Sanford was shelled for all six goals on 38 shots.