Updated

NEW YORK (Reuters) - The National Football League (NFL) will not play a second game in London this year because of the uncertainty of its collective bargaining agreement with players and the economic climate, the league said Sunday.

"Playing one game in the UK is a significant investment," the NFL said in a statement on its website (www.nfl.com). "Playing a second game is an even bigger investment.

London's Wembley Stadium will host this year's only game when the Denver Broncos meeting the San Francisco 49ers in a regular-season contest on October 31.

The league said it still hoped to add a second game in the future.

"Our ambition to bring a second game to the UK is as strong as ever," the NFL said. "Once the current uncertainty is resolved, we will be in a strong position to bring multiple games to our UK fan base."

(Reporting by Gene Cherry in Salvo, North Carolina, editing by Nick Mulvenney)