Boulder, CO (SportsNetwork.com) - Marcus Mariota threw five touchdown passes to lead second-ranked Oregon to a 57-16 drubbing of Colorado at Folsom Field.
Mariota completed 16-of-27 passes for 355 yards and also rushed for a pair of scores for the Ducks (5-0, 2-0 Pac-12), who have won each game this season by at least 39 points.
Bralon Addison caught five passes for 158 yards and two touchdowns, Josh Huff finished with five catches for 103 yards and two scores and Byron Marshall picked up 122 yards on the ground in the win.
"I didn't really think about mercy," Oregon head coach Mark Helfrich said. "That's a good program, a proud program. We're not in the embarrassment business. We're not in the statistic business and we don't think about individual awards. That's not our deal. We just wanted to get in a rhythm offensively."
Connor Wood was 11-for-33 passing for 205 yards and two interceptions. Paul Richardson finished with 134 yards receiving and also threw a 75-yard touchdown pass for the Buffaloes (2-2, 0-2), who have dropped back-to-back games.
Colorado jumped out to an early lead as Will Oliver booted through a 33-yard field goal.
The Ducks, though, answered back just over two minutes later as Mariota ran it in from two yards out. Pharaoh Brown bulled his way across the goal line for the two-point conversion to make it 8-3.
The Buffs got creative on their next touch as Richardson took a pitch on a reverse then found D.D. Goodson wide open along the right sideline for a 75- yard touchdown.
Oregon, however, added three touchdowns before the end of the first quarter to blow the game wide open.
First, Thomas Tyner ran it in from two yards out, and Mariota followed with a 75-yard touchdown strike to Addison.
After Wood was picked off by Terrance Mitchell on the Colorado 26, Mariota connected with Keanon Lower for a 17-yard score to make it 29-10.
Oliver added a pair of field goals early in the second, but Mariota tacked on two more touchdowns to close out the half.
"I felt like if we would've kept coming away with nothing, I felt it might have deflated us," MacIntyre said. "I felt the field goals us a little bit of energy."
The sensational sophomore capped a 12-play, 67-yard drive with a 1-yard TD plunge before orchestrating an 11-play, 92-yard march which ended in a 4-yard toss to Huff for a 43-16 lead heading into the break.
Mariota found Addison for a 44-yard touchdown 4:21 into the second half for a 50-16 cushion before adding a 26-yard TD strike to Huff just under four minutes later.
Mariota hasn't thrown an interception since Nov. 17, 2012 ... Mariota has 14 passing touchdowns and seven rushing TDs this season ... Oregon outgained Colorado in total yards by a 755-374 margin ... The Ducks will have their first test of the season next week as they visit No. 15 Washington ... The Buffs will visit No. 22 Arizona State next week.