Nashville, TN – Doron Lamb scored 16 and his three-pointer 63, for their 17th straight win.
The Wildcats scored the final eight points, blanking Vanderbilt over the final four minutes.
Tinsley's jumper provided Vandy with a 63-61 edge with 4:10 left, but the Commodores went cold from the field the rest of the way, missing their final nine shots.
Lamb's three with 3:18 to go gave Kentucky the lead for good and Michael Kidd- Gilchrist added a pair of free throws with 2:08 left to make it a 66-63 difference.
Ezeli then missed a jumper and Taylor was off the mark on the following shot.
The Wildcats essentially sealed the win with a circus play at the other end. Kidd-Gilchrist dribbled into the lane before losing his footing, but somehow passed the ball from his knees to Darius Miller, who made an acrobatic layup just before the shot clock expired with 1:13 remaining.
Missed free throws from Teague and Kidd-Gilchrist opened the door for Vandy, but the Commodores continued to miss the mark in the closing seconds.
Jones jammed off an assist from Lamb, and then hit a jumper to cap a run of eight straight points for the Wildcats to give them a 20-11 advantage. A jumper from Jones provided a 34-20 lead with 1:27 left in the half and the margin stood at 13 at the break.
A three-pointer from Jenkins capped a 9-2 push for Vandy, getting the hosts within 44-41 with 14:08 left. The Commodores pulled even at 48 following a three-ball from Taylor barely inside 12 minutes left.
Kentucky's defense forced Vanderbilt into 28 percent shooting in the first half; its lowest first half showing of the year. Vanderbilt ended at 36.5 percent shooting...Kentucky was 3-of-14 from three-point range...Kentucky is 70-1 under John Calipari when holding an opponent to 67 points or fewer...The Wildcats held a 44-22 scoring advantage in the paint.