The best-of-five affair will be staged on red clay at Forum Fribourg.
Fish-Wawrinka will be followed by a bout between Swiss great Roger Federer and 6-foot-9 American John Isner. This will mark the 16-time Grand Slam champion Federer's first World Group Davis Cup action since 2004, as he has played in only a few playoffs and zonal matchups since then.
Saturday's doubles will pit an American tandem of Mike Bryan and Ryan Harrison against a powerful Swiss pairing of Federer and Wawrinka, who were the gold medal winners at the Olympic Summer Games in Beijing in 2008. Bob Bryan made himself unavailable to play doubles for the U.S. this week after his wife gave birth to their first child last week.
Sunday's reverse singles will pit the former world No. 1 and currently third- ranked Federer against the No. 8 Fish and Wawrinka versus Isner.
The 32-time Davis Cup champion Americans will play this week without injured star Andy Roddick.
The U.S. is 2-1 all-time versus Switzerland, including a victory in the final back in 1992. The Swiss, however, are 1-0 all-time against the Americans on home soil, with the victory coming 11 years ago in Basel.
Team USA is captained former world No. 1 star Jim Courier, while Switzerland, which has never captured the Davis Cup, is led by Severin Luthi.
The USA-Switzerland winner will meet the Canada-France victor in the quarterfinals in April.