Drew Brees, DeMarco Murray and Luke Kuechly are among the inactives for Sunday's NFL games.
When New Orleans visits Carolina, the Saints will be without Brees at quarterback because of injury for the first time since 2006. Brees is sidelined with a shoulder injury.
For the Panthers, their star linebacker Kuechly is out because of a concussion.
Philadelphia lines up against the New York Jets without Murray, the star running back who came over from Dallas this season who is out with a strained hamstring. He has been limited to 11 yards on 21 carries in his first two games with the Eagles.
Among the actives are running back Todd Gurley for the Rams, quarterback Geno Smith for the Jets.
NEW ORLEANS AT CAROLINA
Saints: QB Drew Brees, DB Keenan Lewis, S Jairus Byrd, DE Obum Gwacham, LB Dannell Ellerbe, DE Kaleb Eulls, G Jahri Evans
Panthers: LB Luke Kuechly, RB Brandon Wegher, OT Daryl Williams, WR Kevin Norwood, WR Jerricho Cotchery, S Dean Marlowe, DT Colin Cole.
OAKLAND AT CLEVELAND
Raiders: CB Dexter McDonald, FB Jamize Olawale, OL Jon Feliciano, OL Matt McCants, DT Justin Ellis, WR Rod Streater, DE Benson Mayowa.
Browns: QB Austin Davis, RB Robert Turbin, DB K'Waun Williams, LB Scott Solomon, WR Dwayne Bowe, TE E.J. Bibbs, DL Desmond Bryant.
PITTSBURGH AT ST. LOUIS
Steelers: QB Landry Jones, CB Cortez Allen, LB Ryan Shazier, DT Daniel McCullers, G-C Chris Hubbard, TE Jesse James, DE Caushaud Lyons.
Rams: RB Isaiah Pead, RB Chase Reynolds, DE Eugene Sims, QB Sean Mannion, OT Andrew Donnal, G Cody Wichmann, WR Brian Quick.
PHILADELPHIA AT NEW YORK JETS
Eagles: RB DeMarco Murray, LB Kiko Alonso, DE Cedric Thornton, LB Mychal Kendricks, DE Taylor Hart, WR Josh Huff, QB Thad Lewis.
Jets: WR Eric Decker, WR Chris Owusu, CB Darrin Walls, LB Trevor Reilly, OL Jarvis Harrison, OT Ben Ijalana, NT Deon Simon
JACKSONVILLE AT NEW ENGLAND
Jaguars: WR Denard Robinson, CB Dwayne Gratz, S Johnathn Cyprien, OT Luke Joeckel, TE Julius Thomas, DE Andre Branch, DT Sen'Derrick Marks.
Patriots: CB Bradley Fletcher, DB Tavon Wilson, RB Travaris Cadet, TR Michael Hoomanawanui, LB Rufus Johnson, OL Ryan Wendell, DL Trey Flowers
SAN DIEGO AT MINNESOTA
Chargers: WR Jacoby Jones, CB Brandon Flowers, RB Donald Brown, S Jahleel Addae, LB Tourek Williams, G Johnnie Troutman, TE Ladarius Green
Vikings: QB Taylor Heinicke, WR Stefon Diggs, CB Jabari Price, LB Edmond Robinson, G Zac Kerin, TE Chase Ford, DE Danielle Hunter
CINCINNATI AT BALTIMORE
Bengals: WR Greg Little, WR Mario Alford, CB Chris Lewis-Harris, TE Marcus Hardison, DE Pat Sims, DE Margus Hunt.
Ravens: WR Breshad Perriman, CB Tray Walker, CB Will Davis, LB Jason Babin, T Eugene Monroe, DT Christo Bilukidi, DE Chris Canty.
ATLANTA AT DALLAS
Falcons: WR Devin Hester, RB Tevin Coleman, WR Justin Hardy, OLB Brooks Reed, C Gino Gradkowski, T Bryce Harris, T Jake Long
Cowboys: QB Matt Cassel, RB Christine Michael, TE Geoff Swaim, G Ron Leary, DE Jeremy Mincey, DE Randy Gregory, WR Dez Bryant
INDIANAPOLIS AT TENNESSEE
Colts: CB Darius Butler, CB Greg Toler, OLB Trent Cole, G Lance Louis, DT T.Y. McGill, OT Denzelle Good, TE Dwayne Allen.
Titans: CB Jason McCourty, QB Charlie Whitehurst, RB Terrance West, CB Cody Riggs, RG Chance Warmack, TE Chase Coffman, NT Sammie Hill.
TAMPA BAY AT HOUSTON
Buccaneers: QB Ryan Griffin, WR Adam Humphries, RB Mike James, S Major Wright, C Evan Smith, OL Matthew Masifilo, TE Austin Seferian-Jenkins.
Texans: WR Jaelen Strong, RB Arian Foster, S Lonnie Ballentine
AP NFL website: www.pro32.ap.org and www.twitter.com/AP-NFL