ROCHESTER, N.Y. (AP) -- Buffalo Bills coach Rex Ryan says defensive tackle Jarius Wynn could be lost for the season after a serious ACL injury.

Ryan called the injury "devastating" to both the Bills and Wynn, and said that Wynn will miss the season if an ACL tear is confirmed.

Wynn was injured in Friday's preseason opener against Carolina. He played 11 games for the Bills last season, picking up two sacks and 17 tackles.

Wynn was entering his eighth season. He has 10 sacks between Buffalo, Green Bay, Dallas, San Diego and Tennessee.

Ryan also said running back Bryce Brown has a minor hamstring injury and may not play in Thursday's preseason game against Cleveland, though wide receiver Percy Harvin should debut for the Bills.

Buffalo also added kicker Dan Carpenter to the active roster, moving him off the active/non-football injury list.