Rep. Ronny Jackson, who was a White House physician to multiple presidents, is circulating a letter among House Republicans demanding that President Biden take a cognitive test or drop out of the 2024 presidential election race

Jackson, R-Texas, led previous calls for Biden to take a cognitive test, including one in July 2022 that was signed by more than 50 House Republicans. The latest letter. first obtained by Fox News, comes as Biden announced Tuesday morning that he will seek reelection.

"We call on you to either resign immediately and renounce your bid for reelection or submit to a clinically validated cognitive screening assessment and make those results available to the public," Jackson's letter, which is addressed to Biden, says. 

U.S. President Joe Biden speaks during a State of the Union address

President Biden announced Tuesday morning that he is running for reelection. (Jacquelyn Martin / AP / Bloomberg via Getty Images / File)

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The letter cites Biden's age, public gaffes and polls showing many Americans have doubt about the president's mental fitness as reasons for the president to take a cognitive test. Fox News is told the deadline for other Republicans to sign onto the letter is Wednesday. 

"When you first announced your bid to run in the 2020 presidential election, questions and concerns were raised surrounding your cognitive abilities. Those concerns have only increased because your mental decline and forgetfulness have become more apparent since you were elected," Jackson wrote in the letter.

Ronny Jackson at CPAC

Rep. Ronny Jackson, R-Texas, is a former White House physician.  (Elijah Nouvelage / Bloomberg via Getty Images / File)

"The American people should have absolute confidence in their President and know that he or she can perform their duties as Head of State and Commander in Chief," Jackson also said. "Therefore, the American people deserve complete transparency on the mental capabilities of their highest elected leader."

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The Biden administration has repeatedly brushed aside concerns about Biden's acuity. Earlier this year when GOP presidential candidate Nikki Haley proposed that politicians over 75 take mental competency tests, White House press secretary Karine Jean-Pierre said attacks on Biden over his fitness for office failed in the past.

"You know, we’ve heard these types of attacks or remarks before. And, you know, if you go back to 2020, they said that the president couldn’t do it in 2020 and attacked him there, and he beat them," Jean-Pierre said. "Maybe they’re forgetting the wins that this president has had over the last couple of years. But I’m happy to remind them anytime."

Biden's lack of interviews with news outlets has also fueled speculation that the White House is playing it safe with Biden in potentially hostile environments. According former CBS White House correspondent Mark Knoller, Biden had granted 33 total interviews as president as of Feb. 8. Trump was at 147 at that point in his presidency, according to Knoller, while Obama was at 273. 

Biden Baltimore

President Biden has done fewer sit-down interviews with the press than his recent predecessors, but the White House argues that he has been available to reporters through other means. (Drew Angerer / Getty Images / File)

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The White House this month, however, argued that Biden in the first 20 months of his presidency engaged with the press in more question-and-answer sessions, including informal exchanges, than his two immediate predecessors combined.

During one of those informal exchanges Monday, Biden appeared to tease a 2024 presidential announcement.

"I told you I’m planning on running. I’ll let you know real soon," Biden said. He jumped in the race less than 24 hours later. 

Fox News' Patrick Ward, Jacqui Heinrich and Sarah Tobanski contributed to this report.