The plane was able to safely land at Daniel K. Inouye International Airport and no injuries were reported, FOX station KHON-TV in Honolulu reported.
The plane was met on the tarmac with a large police and first responder presence.
Videos on social media appeared to show a huge fireball coming from the plane while it was still in the air.
The flight had left from Hickam Air Force Base only a few miles away in Honolulu, the Hawaii Department of Transportation said, according to KHON.
The station reported other Honolulu residents said they heard an explosion and saw a bright light.