The 56-year-old actor, who won a VGA for voicing "Grand Theft Auto: San Andreas," (search) will host the Nov. 18 awards show at the Gibson Amphitheater in Los Angeles. The show will air Dec. 10 on Spike TV.
"Sam Jackson is one of the coolest guys on the planet; we're thrilled to have him hosting this year's show which promises more stars, more rock and more games than ever before," said Casey Patterson, senior vice president, event production and talent development for Spike TV, in a statement this week.
The Red Hot Chili Peppers, Vin Diesel, The Rock, Missy Elliot, Snoop Dogg and Ozzy Osbourne are among those set to appear at the third annual awards event.
Jackson was nominated for an Oscar for his role in 1994's "Pulp Fiction." He has also appeared in "A Time to Kill," "Shaft" and "Changing Lanes."