Updated

Tom Brady was listed as questionable Friday for the New England Patriots' game at Buffalo on Sunday because of an ankle injury.

The quarterback was listed as having limited participation in practice Friday. He wasn't on the club's injury report Wednesday or Thursday.

Brady hasn't missed a game since a season-ending knee injury in the 2008 opener. He had his best game of the season Sunday night, throwing for 292 yards and two touchdowns in a victory over Cincinnati.

Rookie Jimmy Garoppolo is Brady's backup.