Detroit, MI – Johnny Giavotella knocked in three runs and 5, to open a four-game set.
Salvador Perez went 3-for-4 with a solo home run and two RBI in Kansas City's third win in five games.
Luke Hochevar (9-10) pitched into the eighth inning, allowing five runs on eight hits and two walks while fanning seven to snap a four-start winless skid.
Miguel Cabrera had three hits, knocked in a run and crossed the plate once as the AL Central-leading Tigers dropped their second straight contest.
Max Scherzer (13-8) was touched for seven runs on 10 hits and a walk through just three-plus innings for the loss.