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(SportsNetwork.com) - The San Antonio Spurs will try not to look ahead to an upcoming showdown with LeBron James and the Cleveland Cavaliers when they host the only winless team in the NBA Monday, the Philadelphia 76ers.

The Spurs and Cavs will tangle Wednesday at Quicken Loans Arena, but San Antonio has to take care of business at home versus the 76ers.

San Antonio went 3-1 on a recent road trip and had a three-game winning streak stopped with Saturday's 94-91 loss to the Sacramento Kings.

Manu Ginobili scored 21 points off the bench and both Danny Green and Kawhi Leonard posted 16 points. Tim Duncan had 15 points and eight rebounds for the Spurs, who shot 42.5 percent and made only 7-of-24 3-pointers.

"It was still a great road trip," said Spurs point guard Tony Parker, who had 11 points and six assists. "We wanted to be greedy and go 4-0, but 3-1 -- especially with the Clippers and Golden State back-to-back -- it's tough to do, especially with all (our) injuries."

The Spurs are last in the Southwest Division.

Philadelphia knows a lot about last place and currently resides in the basement of the Atlantic Division.

The 76ers will wrap up a four-game road trip and a three-game tour of Texas Monday, and suffered a tough 88-87 loss in Houston on Friday. It came just one night after falling by 53 to the Dallas Mavericks.

Rockets star James Harden made a go-ahead layup with 9.0 seconds remaining, and Michael Carter-Williams missed a potential game-winner at the buzzer to end a surprisingly tight contest.

"I'm proud of how the guys played," said Carter-Williams, who had 13 points, five assists and five rebounds. "Everyone contributed. Everyone made big plays down the stretch."

Tony Wroten led the visitors with 19 points and Henry Sims scored 14 for Philadelphia, which started 0-15 back in 1972-73.

The Sixers are 0-5 on the road this season and will play six of the next seven games in south Philly.

Philadelphia lost both matchups with San Antonio last season and is winless in the past six games in this series. The 76ers have struggled in the Alamo City, losing 10 straight and 26 of the previous 27 trips there.