San Francisco, CA (SportsNetwork.com) - Richard Sherman's two interceptions highlighted a dominant defensive effort, as the Seattle Seahawks routed the San Francisco 49ers, 19-3, in a highly anticipated NFC West Thanksgiving clash.

The outspoken cornerback, whose key defensive stop against San Francisco receiver Michael Crabtree in January's NFC Championship Game helped vault the Seahawks into the Super Bowl, picked off Colin Kaepernick twice as Seattle (8-4) limited the 49ers offense to just 164 total yards.

"Every win is important," Sherman said. "This win is no more important than any other win this season."

Russell Wilson completed 15-of-22 passes for 236 yards and a touchdown pass to Robert Turbin, Marshawn Lynch ran for 104 yards on 20 carries and Steven Hauschka kicked five field goals for the Seahawks, who have won five of their last six games.

The Seahawks now sit all alone for second place in the NFC West behind Arizona, which owns a 9-2 record heading into its matchup against Atlanta on Sunday.

Kaepernick threw for 121 yards on 16-of-29 passing as the 49ers (7-5) had their three-game win streak come to an end.

"In all areas, they played better team football," said 49ers head coach Jim Harbaugh. "We have to come back and win them all."

After both teams punted on their first two possessions, Sherman intercepted a Kaepernick dart along the right sideline to give the Seahawks the ball inside 49ers territory.

Wilson connected with Doug Baldwin across the middle and two plays later, Turbin caught a 13-yard swing pass and tiptoed into the end zone for a 7-0 lead with 1:29 to play in the opening quarter.

On Seattle's next drive, Wilson scrambled to elude multiple blitzing defenders and hit Tony Moeaki with a 63-yard strike to the San Francisco 2. The 49ers made a goal-line stand and the Seahawks settled for a 21-yard Hauschka field goal.

Hauschka split the uprights again, this time from 36 yards out, to cap a 5- play, 42-yard trek and increase the Seahawks' lead to 13-0 with 5:40 remaining in the first half.

Lynch's 33-yard scamper led to Hauschka's 35-yard field goal for a 16-0 score near the midway point of the third quarter.

he 49ers finally got on the board after Phil Dawson booted a 40-yarder with 1:06 to play in the stanza.

Less than five minutes into the fourth, the Seahawks answered with Hauschka's fourth field goal of the evening, a 46-yarder, which was set up by Lynch's 16- yard run and Jermaine Kearse's 17-yard grab.

Kaepernick moved the ball near midfield on San Francisco's ensuing drive, but Sherman jumped in front of a pass intended for Stevie Johnson to intercept the ball at Seattle's 32 with 7:13 remaining to put the game away.

"I told the sideline 'if they threw it my way, I'd end the game.' And they did," said Sherman.

Game Notes

Seattle ended a five-game skid on the road against San Francisco ... Sherman has 23 interceptions since entering the NFL in 2011, which is eight more than any player over that span ... San Francisco's second-ranked defense entered the game allowing just 300.1 yards per game, but allowed Seattle to total 379 yards ... The Seahawks improved to 12-1 in prime-time games under head coach Pete Carroll since 2010 ... Seattle's defense has given up just two field goals over its past two games.