Texas announced before Friday night's game at Seattle that Kinsler had been activated from the 15-day DL. He is expected to start against the Mariners and pitcher Cliff Lee, set to make his Seattle debut.
The Rangers say Arias has a lower back strain. He started for the 13th time this season at second base on Thursday against the Chicago White Sox.
Arias hit .321 in 17 games while Kinsler was out with a high ankle sprain.
Kinsler injured his right ankle during spring training drills on March 12.