Kelsey Bolte scored 22 points and No. 17 Iowa State used a huge second-half run to beat Nebraska 64-43 on Tuesday night.

Anna Prins added 18 points and 11 rebounds for the Cyclones (13-3, 1-1 Big 12), who fell behind 9-0 and trailed by as many as 11 before regrouping at halftime. Iowa State shot 58.6 percent in the second half and held Nebraska scoreless for 9 minutes while breaking the game open with a 22-0 run.

Iowa State outscored Nebraska 43-17 in the second half.

Lindsey Moore's 13 points led Nebraska (10-6, 0-2), which has lost five of seven. The Cornhuskers led 26-21 at halftime, then missed 23 of their first 28 shots in the second half.

Iowa State started the second half with a 19-4 run to open a 40-30 lead. Nebraska drew to 42-37 on Katya Leick's basket inside, but by the time the Cornhuskers scored again, Iowa State was leading 64-37.

Bolte scored nine points during the big run and made all seven of her second-half shots, including four 3-pointers, after managing only four points in the opening half.