Seattle Mariners starting pitcher Kevin Millwood left Wednesday's 2-1 loss against the Oakland Athletics in the third inning with an injury to his right groin.

He previously suffered an injury to the groin in a 1-0 win over the Los Angeles Dodgers on June 8. Millwood pitched six no-hit innings in that start and the Mariners went on to complete the first combined no-hitter since 2003.

On Wednesday, Millwood's only blemish in 2 2/3 innings was a solo home run off the bat of Coco Crisp. Hisashi Iwakuma took over for Millwood and allowed the game-winning solo shot to Yoenis Cespedes in the seventh inning.

Millwood, 37, is 3-6 this season with a 4.00 earned-run average in 15 starts for Seattle.