Finally! Colts beat Titans for first win

Donald Brown ran for 161 yards, including yard score to put the game away late in the fourth quarter, as the 13 triumph over the Tennessee Titans.

Reggie Wayne caught three balls for 33 yards and a score for Indianapolis (1-13), which won its first game without Peyton Manning under center since December 14, 1997 when Jim Harbaugh led the Colts to a 41-0 win over the Miami Dolphins.

Dan Orlovsky threw for 82 yards and a score on 11-of-17 passing, and middle linebacker Pat Angerer had an interception and a forced fumble.

Chris Johnson ran for 55 yards and caught eight passes for 54 yards for the Titans (7-7), who have lost two straight.

Matt Hasselbeck tried gutting it out on a bum ankle and threw for 223 yards with two interceptions. Jake Locker came on in the fourth quarter and threw for 108 yards and a touchdown on 11-of-16 passing.