McGahee sustained a knee injury which kept him out of practice Wednesday and Thursday. The 30-year-old racked up 111 yards and a touchdown on 20 carries in a 35-32 win at Minnesota last Sunday.
In addition, wideout Eddie Royal was listed as questionable while still fighting off the effects of a concussion which prevented him from practicing at all this week.
Linebacker Von Miller (thumb) was listed as probable. He took limited reps Wednesday and Thursday but was able to fully participate Friday.