Kila Ka'aihue knocked in the game-winning run as part of a three-run bottom of the 14th, leading the Oakland A's to a 5-4 win over the Chicago White Sox in the finale of a three-game series on Wednesday.

Ahead, 4-2, going into the bottom of the frame, White Sox closer Hector Santiago (0-1) got off to a good start by striking out Eric Sogard, but then gave up five consecutive hits.

Josh Reddick started the hit parade with a single up the middle and Yoenis Cespedes followed with a moonshot home run to left field to tie the game 4-4. Seth Smith and Kurt Suzuki then stroked back-to-back singles and Ka'aihue ended the game in walkoff fashion with a flare to left field that fell in fair territory to give Oakland the win.

"A win is a win, we'll take them however they come," Ka'aihue said. "At the end of the year they all count the same, so, it's a good team win, the guys played hard and it was awesome."

Jim Miller (1-0) recorded the final out in the top of the 14th to pick up the win for the A's, who have won three of their last four games.

Cespedes went 3-for-5 with three RBI and Suzuki added three hits in the victory.

Chicago's Paul Konerko tied the game in the ninth inning with a momentous solo home run -- the 400th of his 16-year career.

"Every time you get to one (a milestone), you never think you're going to get to the next one," Konerko said. "Yeah, it's cool, but I'll tuck it away now and probably look at it again when I'm done playing."

Alex Rios finished 3-for-5 with two doubles and a run scored and Alexei Ramirez added a two-run double for the White Sox, who have dropped two straight since a four-game winning streak.

Trailing, 2-1, the White Sox tied the game at two in the ninth when Konerko took the first pitch he saw from Grant Balfour -- a high fastball -- deep over the left field wall.

Chicago had a golden opportunity to take the lead in the 11th after A. J. Pierzynski nubbed a ball out in front of the plate. A's pitcher Jordan Norberto threw the ball away, allowing Pierzynski to get all the way to third with two outs. Norberto intentionally walked Rios then fanned pinch-hitter Dayan Viciedo to end the inning.

The White Sox squandered multiple opportunities to take the lead in the 13th. Adam Dunn led off the frame by ripping a double down the right field line, and Konerko was then intentionally walked. Dunn was replaced at second by pinch- runner Brett Lillibridge and Konerko was replaced by Gordon Beckham.

Lillibridge was picked off at second by a perfect throw from Suzuki for the first out, and after Pierzynski popped out, Rios ripped a double down the left field line, but Beckham was thrown out at the plate to keep the game tied.

Chicago took the lead in the top of the 14th after Viciedo reached on a throwing error by Sogard and Alejandro De Aza walked to put two runners on base. Ramirez then brought them both home with a double into the left-center field gap.

Earlier, Oakland finally broke the scoreless tie in the sixth. After Daric Barton fouled out to start the frame, Jemile Weeks slapped a single to left and scored from first on a double to deep center by Reddick to put the A's up 1-0. Oakland added a second run in the inning on a single up the middle by Cespedes which scored Reddick for a 2-0 edge.

Chicago quickly got one back in the seventh after Rios ripped a single and came around to score on a double into right-center by Kosuke Fukudome, who then advanced to third on the throw. A's manager Bob Melvin then brought in Ryan Cook from the bullpen. With Brent Morel at the plate, Fukudome was tagged out trying to steal home, and Morel struck out to end the inning.

Game Notes

Konerko became the third player to hit their 400th career homer in a White Sox uniform, joining Frank Thomas and Andruw Jones. He also became the 48th player to join the 400-home run club...A's starter Jarrod Parker, who was called up from Triple-A Sacramento on Wednesday along with Miller, tossed 6 1/3 strong innings, giving up just one run on seven hits and a walk while fanning five...Chicago starter Chris Sale gave up two runs on six hits and no walks while striking out five over eight innings.