President Obama will meet with Israeli Prime Minister Benjamin Netanyahu and Chinese Premier Li Keqiang while they are in New York this week for the U.N. General Assembly.

Obama and Netanyahu are scheduled to talk Wednesday, about a week after the United States and Israel signed a new, unprecedented security agreement that will give the Israeli military $38 billion over 10 years.

It's the largest such agreement the U.S. has ever had with any country.

The White House says the leaders will discuss advancing the so-called “two-state solution” to the Israeli-Palestinian conflict and the Iran nuclear deal, which Netanyahu vehemently opposed.

Obama is expected to meet Monday with Keqiang to discuss U.S.-China relations and North Korea. He leaves for New York on Sunday afternoon, amid tightened security after a bomb was detonated Saturday night in midtown Manhattan, wounding 29 people.

The Associated Press contributed to this report.