Updated

WASHINGTON - The fate of efforts to enact sweeping changes to the nation's health care system may come down to whether two moderate New England Republicans, Maine Sens. Olympia Snowe and Susan Collins, can be brought on board.

Sens. Snowe and Collins played a pivotal role in passing the $787 billion economic-stimulus package, joining Democrats to provide the key votes, along with Republican-turned-Democrat Arlen Specter of Pennsylvania.

Now Republican leaders are lining up to oppose health care legislation. And getting Sens. Snowe and Collins to cross party lines will be crucial, if the White House has any hope of enacting a bill that meets the president's goal of extending insurance coverage to tens of millions of Americans.

"If you're looking for Republicans who might compromise, the two Maine senators are definitely ones he'll have to look to," said Rep. Mike Michaud, D-Maine. "Democrats will not all be on same page. So he's going to have to pick up the losses elsewhere."

So far, Sen. Snowe is carving a higher profile on the health issue. She is part of a group known as the Gang of Six, three Republicans and three Democrats from the Senate Finance Committee who are trying to piece together a bipartisan plan. She has suggested a willingness to possibly support a trigger that would establish a public insurance plan if other proposals in the bill fail to expand private insurance coverage sufficiently.

Sen. Collins isn't directly involved in negotiations, but is eager to see what the discussions come up with, according to spokesman Kevin Kelley. Sen. Collins doesn't favor a public option. She also wants to hold down the cost of the bill and reduce the cost of insurance to individuals.

Click here to read the full story at the Wall Street Journal.