Updated

Luke Bryan thanked his fans for their prayers after revealing his infant niece Sadie Brett Boyer died Tuesday. Boyer was born in the summer of 2016 and was battling an undisclosed cardiac heart issue as well as several other conditions.

Boyer was the daughter of Luke Bryan's wife Caroline's brother Bo Boyer and his wife Ellen Boyer.

LUKE BRYAN OPENS UP ON RAISING NEPHEW AFTER PARENTS' DEATH

Bryan tweeted to his fans Tuesday evening, "We thank all of you for your prayers. Love y'all."

The family stayed relatively quiet about the baby's condition, however, Bryan shared several updates on his app about her condition. Two months ago, Bryan revealed his niece was undergoing treatment at Vanderbilt Children’s Hospital in Nashville, according to Taste of Country.

11 COUNTRY MUSIC LEGENDS WHO LEFT US TOO SOON

This is not the first tragedy to strike the Bryan family. Bryan's older brother, Chris, died in a car accident at age 26. His sister, Kelly, died unexpectedly in 2007 at age 39. Her husband, Ben Lee Cheshire, died in 2014 and Bryan and his wife Caroline took in their nephew Til.